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Platelets in inflammation and atherogenesis

Consider circadian variations for neuroendocrine measurements

After first centrifugation, plasma and buffy-coat layer were removed, and RBCs were washed twice by centrifugation at 400 g for 3 min (Centrifuge ELMI-50CM, Riga, Latvia) and resuspended in HEPES-buffer

Allosteric modulators Allosteric modulators typically attach to regions distinct from the orthosteric site of receptors, inducing conformational changes to regulate the affinity and/or efficacy of orthosteric ligands, or to directly modulate receptor activity with positive, negative, or neutral effects