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In this report a recommendation was made that toxicity tests should be used, not to attempt to reproduce field exposures, but to develop a consistent means of using toxicity metrics, such as HC 5 and LC 50 for toxicity models used with fate and transport models to compare the exposure and toxicity of various response options, including dispersants (NASEM, 2020)

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However, it is interesting that the release of oxidized nucleobases (e.g., 8-OHG) can activate the STING1-mediated inflammatory response in macrophages [259]