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They reported finding no genetic regions of loci associated with MVD, and they concluded that: "This analysis suggests that familial occurrence of mitral valve murmur in the CKCS breed is not due to a single major gene effect, indicating that breeding strategies to eliminate the disease cannot be based on genotype information at this time." In a December 2017 article, a team of 10 American cardiologists and geneticists examined the DNA in 10 cavaliers and 10 dachshunds diagnosed with MVD, searching for varients of genes known to be analogous to genetic mutations associated with MVD in humans

doi: 10.1186/s12944-018-0939-6 71 TousoulisDOikonomouEEconomouEKCreaFKaskiJC

In agricultural contexts, livestock that grazed on selenium-rich soils developed characteristic poisoning syndromes

[15] What are the most important counseling points for outpatients discharged with an oral continuation course