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Supplementary material The Supplementary Material for this article can be found online at: References 1 AnH.ZhaiZ.YinS.LuoY.HanB.HaoY

In, CNS affected patient, EVs are used for administering drugs directly to the brain (139) and for deliveries across the blood-brain barriers (140)

Nat Neurosci 4 : 702710 This is the one of the earliest papers to propose a new pathway for glia-glia and glia-neuron communication that is relevant to both normal brain function and neurodegenerative diseases