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Similar content being viewed by others Introduction Many conventional cancer therapies often lead to undesired side effects because they target proteins and cellular processes necessary for normal cell survival and proliferation, including various progenitor cell types

Protective treatment approaches aimed at restoring the NADH/NAD ratio also include increasing flux to parallel pathways such as the pentose phosphate pathway [57, 70], Krebs cycle (TCA) and oxidative phosphorylation (Fig