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The latter is not yet targeted by approved drugs according to currently available databases and might therefore be interesting for drug repurposing efforts

The core members of the auxin signal transduction mechanism are composed of three protein families which are used as auxin coreceptors: transport inhibitor response1/auxin signaling F-box protein (TIR1/AFB), auxin/indole-3-acetic acid transcriptional repressor (Aux/IAA) and auxin response factor (ARF) [67]

Although this classification is based on the primary sequences, the recent release of several plant genomes allowed for its correlation with the intron-exon structure of GST-encoding genes as analyzed in P

Vitamin A supplementation above 5,000 IU/day causes additive hypervitaminosis A toxicity [13]