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With further research into statins, it has been discovered that statins may protect the cardiovascular system through mechanisms independent of lipid-lowering, referred to as pleiotropic effects (72)

Beyond, it seems that there is an inverse relationship between Oscillibacter (a genera increased in patients with BD) and the levels of tryptophan and KYNA, thereby supporting the relevance of gut microbiota in the altered Kyn pathway and neuroinflammation [235]