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doi: 10.1073/pnas.1322003111

The combination of 40 M astragaloside IV and 2 M cisplatin (neither concentration exhibiting significant toxicity to HepG2 cells) significantly decreased the cell viability, induce tumor cell apoptosis, slow down the growth of tumor cells both in vitro and in vivo, and improve the chemosensitivity of liver cancer cells to cisplatin by reversing the overexpression of multidrug resistance-associated protein MRP2 in tumor cells induced by cisplatin

Recht junge Gen-Forschungen zeigen zudem, dass Europer hufig Mutationen im Carnitin-Transporter-Gen (OCTN2) haben, was den Carnitinbedarf bei jenen Menschen mglicherweise erhht, die diese Polymorphismen tragen (2)

Gold Standard 2016a): palonosetron (Aloxi), a 5-HT 3 receptor blocker oral aprepitant or intravenous fosaprepitant (Emend), a neurokinin-1 receptor blocker ondansetron (Zofran) Typically, a single intravenous dose of palonosetron is given 30 minutes prior to chemotherapy to prevent nausea and vomiting