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Seine Plasmakonzentration liegt bei jungen Erwachsenen (etwa 20 Jahre) bei circa 200 ng/ml, sinkt aber bis zum Alter von etwa 60 Jahren auf rund 80 ng/ml

doi: 10.1016/j.abb.2008.11.017

Reactome enrichment and GSEA analysis further intuitively demonstrated the significant activation of the pyroptosis signaling during ALI (Figure 1B, 1C)

With the understanding of disease pathogenesis, patient-focused novel interventions that correct fundamental metabolic imbalances, such as enzyme replacement, gene therapy and RNA-based treatments, have become important (2)