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45 minutes Ozone therapy is an Intravenous infusion treatment that involves the administration of ozone gas into the body to treat various medical conditions

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This method bypasses the digestive system, ensuring that the body absorbs the maximum amount of nutrients

Importantly, converging clinical and preclinical data support a bidirectional interplay whereby circadian disruption and sleep disorders not only emerge early in the disease course, but also aggravate neurodegenerative processes and deeply affect the quality of life of patients and caregivers, underscoring the potential of circadian-based interventions as disease-modifying strategies [13]