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Homologous recombination repair requires homologous chromosomes as templates and repairs broken DNA through a series of precise pairing and exchange steps

However, ROS may have a cytotoxic effect to cancer cell if the ROS reaches a certain threshold level 56

Due to the complex interaction of different factors that contribute to an effective immune response, there may be more than one correlate of protection, and the mechanisms of protection during natural infection may differ from those seen after vaccination

Taken together this indicates that Gsta4 reduces Fas-Casp8 signaling in differentiating OLs, which might regulate not only their survival but also their differentiation