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Inflammatory mechanisms in Parkinsons disease: from pathogenesis to targeted therapies

doi: 10.1021/acs.jafc.4c00695

Sulforaphanes ability to activate the Nrf2 pathway, a master regulator of cellular defense, underpins its wide-ranging health benefits

In cultured cells, co-expression of jet and cry is sufficient to recapitulate light-induced degradation of tim, suggesting that jet transduces cry-dependent light input to tim (Koh et al., 2006)