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MetZ exhibited stable RMSD values at 2.98 and 4.34 at pH 7.0 and 5.5, respectively, indicating the considerable change in the stability of the substrate as well as the occupied binding site

Berberine ameliorates iron levels and ferroptosis in the brain of 3 Tg-AD mice

Agonists of Nuclear Factor Erythroid 2-Related Factor 2 Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that interacts with Keap1 and is ubiquitinated by Cullin 3 in the cytoplasm prior to its degradation in the proteasome