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This can lead to a profound sense of loss or emptiness, which may lead to suicidal ideation if left untreated

[DOI] [PMC free article] [PubMed] [Google Scholar] 294.Oneta CM, Lieber CS, Li JJ, Rttimann S, Schmid B, Lattmann J, Rosman AS, Seitz HK

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Time Interval Decrease Giving doses more frequently (reducing the time interval) will increase the overall drug concentration, as well, but not the time it takes to reach steady state.