glutathione s transferase a1 S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl–dithiolato iron complexes in cells Glutathione transferases as mediators of

Stable Isotope Tracing (13C-Met) : Tracking methionine metabolic flux showed a 30% reduction in methionine-to-SAM conversion efficiency in the cachexia model, with no compensatory upregulation of the transsulfuration pathway (generating Cys and GSH)

Targeting USP8 inhibits O-GlcNAcylation of SLC7A11 to promote ferroptosis of hepatocellular carcinoma via stabilization of OGT

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

For instance, the depletion of short-chain fatty acids (SCFAs) promotes the polarization of M1 macrophages, which drives intestinal inflammation [36]