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Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma

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The net effect in cell culture is increased deposition of structurally mature extracellular matrix

TB-500 derives from thymosin beta-4, which regulates actin and is described in the published profile of thymosin beta-4 as a regenerative peptide as a driver of cell movement, new vessel formation, and reduced scarring