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ROS-producing bacteria have even been implicated in the pathogenesis of colon cancer, which induce aneuploidy (genomic instability) in normal colonocytes via a bystander effect. 66 Likewise, H

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Moreover, the invasion of cancer cells and resistance to multi-kinase inhibitors regorafenib and sorafenib were also associated with increased IGF-1R signaling in metastatic colorectal cancer and hepatocellular carcinoma (4345)

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