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Similar content being viewed by others Introduction Schizophrenia is a psychotic disorder that is characterized by significant loss of function and continues to constitute a significant disease burden globally [1]

Neuro Endocrinol Lett 32(2):133140 Maes M, Fiar Z, Medina M et al (2012) New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways

Disruptions in circadian rhythms can adversely affect sleep quality and lead to imbalances in gut microbiota, resulting in alterations to the community structure, ecological parameters of the microbial ecosystem, and the inflammatory state of the body [45, 214,215,216,217,218,219,220,221]

HNSCC in the oral cavity and larynx are usually treated with surgical removal of affected tissues which is then followed by adjuvant radiation or chemotherapy along with radiation known as chemoradiotherapy (CRT) [56]