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Treatment depends on whether the pain is caused by vascular compression near the brainstem, irritation of trigeminal nerve branches in the face, dental or surgical injury, viral nerve damage, central sensitization, or overlapping contributing factors

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There was no significant difference in the cytotoxic effects of 3-BP between cetuximab-resistant cell lines (HCT116(KRAS G13D/- ), DLD-1(KRAS G13D/- ), HT29(BRAF V600E ), RKO(BRAF V600E/-/- ), Caco-2-CR) and their paired cetuximab-sensitive cell lines (HCT116(KRAS wt/- ), DLD-1(KRAS wt/- ), HT29(shBRAF), RKO(BRAF wt/-/- ), Caco-2), indicating that the cytotoxic effect of 3-BP in these CRC cell lines is independent of their response to cetuximab

Anal Chem 86:1145111458 Wang Y, Lu M, Zhu J, Tian S (2014) Wrapping DNA-gated mesoporous silica nanoparticles for quantitative monitoring of telomerase activity with glucometer readout