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"Several liver diseases like acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also be accompanied by an increase in circulating cobalamin," according to the aforementioned researchers

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The GAO conducted the required surveys in 2004 and 2005, and, in reporting the results in 2006, recommended that the Secretary thereafter validate, on an occasional basispossibly every 5 or 10 yearsaverage sales price (ASP) data that manufacturers report to CMS for developing SCOD payment rates. [527] CMS has not, however, conducted its own survey of the acquisition costs for each SCOD for all hospitals paid under the OPPS