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There is an extensive interaction between the KP and the immune system 26,27,28

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Low-pressure burst-mode transcranial focused ultrasound (FUS) exposure with the presence of microbubbles can locally, temporally and reversibly open the BBB 4

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Reinvigorating T cell exhaustion The major limitation in GBM immunotherapy is T cell exhaustion, which results from chronic antigen exposure and leads to a progressive decline in CTL function

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