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Cancer Cell 39 , 586589 (2021)

Zinc is known to have concentration-dependent effects on ACE-2 activity as it has low affinity-binding sites for zinc ( in-vitro and human clinical studies demonstrate the antiviral activity of zinc such as inhibiting coronavirus Rdrp template binding/elongation and reduction in outbreak recurrence in the case of herpes simplex virus in human subjects ( Effect of antioxidant molecules on SARS-CoV-2 The antioxidant enzyme SOD breaks the toxic oxygen molecules (O 2