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In addition, activation of A2AR signaling using the A2AR-selective agonist CGS 21680 increased T cell survival with addition of exogenous GSH (Supplemental Figure 5, E and F)

We saw some improvement in disease severity but not enough to justify the risks for most patients. While the study showed that most patients should not undergo the procedure, the data hint that the benefits may outweigh the risks in some patients, such as those with exceptionally large clots