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However, under certain conditions, in the presence of free (unbound) redox metals, such as iron or copper, resulting from metal dyshomeostasis, vitamin C may exhibit prooxidant properties Prooxidant properties of vitamin C in the presence of redox-active metal ions and oxygen have been confirmed predominantly under in vitro conditions, occurrence under in vivo conditions has not been convincingly documented (Halliwell 1996)

Prostandin 16

Typically, patients are given drugs to suppress and turn down these auto-immune responses and that can work for a while, but over time, the treatments can cease to be effective

Details of the search strategy can be found in Supplementary File 1