glucorindation vs glutathione Glucuronidation reaction (a) and preferred chemical structures for Phase II Reactions - Biotransformation

Phase II Reactions Biotransformation of Drugs Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial Phase II Drug Metabolism IntechOpen Mechanistic Studies on the Bioactivation of Diclofenac: Identification of Diclofenac S acyl glutathione in Vitro in Incubations with Rat and Human Hepatocytes Chemical Research in Toxicology

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