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Description

Quiescent T cells predominantly depend on oxidative phosphorylation and fatty acid catabolism for their energy needs ( Upon activation, T cells rapidly enhance their glycolytic machinery, facilitated by a diverse ensemble of enzymes and proteins

The brainstem-cortex network plays a critical role in the migraine pathway, with conditions such as insomnia, obstructive sleep apnea, sleep-related movement disorders, and REM sleep disturbances closely associated with migraine onset (Vgontzas and Pavlovi, 2018)