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Oxidant Dependence of T Cell Activation Oxidative stress is provoked by an imbalance between the production of mitochondrial superoxide and insufficient scavenging of ROS, ultimately resulting in a wide range of pathological conditions ( 2 O 2 )

Due to its hydrophobicity, quercetin has relatively poor solubility in water (0.177 g/ml), gastric fluids (5.5 g/ml) and small intestine fluids (28.9 g/ml), which have reduced its bio-accessibility ( Quercetin can be transported through sodium-dependent glucose transporter 1(SGLT1)

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