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doi: 10.3945/jn.117.254532, 89

As different APOE genotypes are shown to have different energy substrate preferences it is not surprising that L-carnitine administration affected levels of these FAO metabolites differently by genotype (Yassine and Finch, 2020)

Avoid taking it if you have any of the following conditions: Peripheral vascular disease High blood pressure Liver disease from alcoholism (cirrhosis) Diabetes Kidney disease History of seizures Underactive thyroid (hypothyroidism): Taking L-carnitine might worsen symptoms of hypothyroidism