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Despite these promising findings, several challenges remain

The N-terminal domain was exposed to the solvent, whereas the C-terminal helix, called the helical thong, was inserted into a hydrophobic hole in the opposite subunit of the other hexameric ring (Fig

This arrangement results in residue Tyr518 from the oligomerisation loop slotting into a hydrophobic pocket formed by Leu423, Val425, Ile429, and Ile437 of -helix 15 (Supplementary Fig

bliche Gerte fr diese Verwendung umfassen Dosisinhalatoren, die verwendet werden, um Arzneimittel fr die Behandlung von beispielsweise Asthma und einer chronischen obstruktiven Lungenerkrankung zu verabreichen