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Conclusion: Al-CPI modifies the transcriptome of moDC, increasing several transcripts encoding enzymes involved in cholesterol biosynthesis and SREBP signaling

The in vitro release profile showed an initial burst of 29.3 4.0% of entacapone released from PEG-PLGA@Ent in the first 2 h, with a cumulative release of 39.7% over 72 h