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Clinical trials with a single natural compound on cancer Curcumin In a randomized double-blind placebo-controlled trial, patients with liver cirrhosis were randomly divided into two groups to receive 1000 mg/day curcumin or placebo for 3 months, beneficial effects of curcumin supplementation were observed in downregulating disease activity scores and severity of cirrhosis in patients

The measurements of the ferrous iron (Fe 2+ ) were performed using an Iron Analysis Kit (AB83366, Abcam, Cambridge, UK) according to the manufacturer's instructions