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175,176 STATs are phosphorylated and translocated into the nuclear compartment to transcriptionally upregulate specific genes, 177 often leading to cell proliferation or differentiation

Pinna A, Ragaisyte I, Morton W, Angioletti-Uberti S, Proust A, DAntuono R, Luk CH, Gutierrez MG, Cerrone M, Wilkinson KA, Mohammed AA, McGilvery CM, Surez-Bonnet A, Zimmerman M, Gengenbacher M, Wilkinson RJ, Porter AE

Although AVE significantly alleviated MMS-induced toxicity, some residual damage persisted, suggesting that it cannot completely counteract genotoxic stress at the tested concentrations

Some peptides with prominent antimicrobial potencies under low-salt conditions lose their activities at physiological salt conditions and/or in serum (due to interactions with serum proteins)