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Immunohistochemical analyses demonstrated that microglia labeled with ionized calcium-binding adapter molecule 1 were commonly positioned in close proximity to degenerating dopaminergic neurons within the substantia nigra

The residues selenium-cysteine (U) or cysteine (C) at the active site, together with glutamine (Q) and tryptophan (W), forms the signature catalytic triad of the glutathione peroxidase family 30

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These studies have focused on the genetic variability of therapeutic targets that could affect cisplatin response and toxicity in diverse type of cancer including lung, gastric, ovarian, testicular, and esophageal cancer