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While such a sharp discrepancy among those studies remains to be solved, different SOD1 antibodies were used for immunohistochemical analysis: a rabbit or sheep polyclonal antibody was raised against a holo form of human SOD1 in the former two studies [66], and a rabbit polyclonal antibody was raised against a SOD1 peptide corresponding to Asp124 to Lys136 in the latter [67]