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In topical skincare and scalp care, it is used as a cosmetic conditioning ingredient

From its purported role in extracellular matrix modulation, gene expression resetting, anti-inflammatory/antioxidant signaling, to tissue repair mechanisms, the peptide provides a unique convergence of metal-ion chemistry, peptide biology, and regenerative mechanisms

GHK-Cu: The Ultimate Skin Regenerator & Collagen Booster GHK-Cu, often called a 'copper peptide,' is my absolute favorite for promoting youthful, resilient skin

This article describes ligand-dependent conformational differences in the calcitonin-receptor-coupled G protein that can modulate the GTP sensitivity of the ternary complex