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The medication's 7-day half-life creates a steady-state plateau by week 45 of therapy, meaning consistent weekly timing matters more than the specific hour of day

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During a three-week treatment period, both Cagrilintide and salmon calcitonin (sCT), another amylin receptor agonist, produced an acute reduction in food intake in WT mice on day 1 by 53% and 42%, respectively, but not in RAMP1/3 KO mice