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Description

447 This condition is most commonly associated with a homozygous unstable guanine-adenine-adenine (GAA) trinucleotide expansion in the first intron of the Frataxin gene (X25) on chromosome

To determine the physiological importance of these functions and sort out those that account for the GSH requirement for viability, we performed a comprehensive analysis of yeast cells depleted of or containing toxic levels of GSH