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24 Stress-induced autophagy and its dual role in cardiac remodeling Autophagy is dynamically activated in response to hemodynamic stress

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Preliminary findings suggest that it may play a role in signaling processes associated with circulation dynamics in controlled settings

Loss of PON1 also reduces HDLs ability to prevent oxidation of its own lipids and proteins, which has been reported in metabolic syndrome as oxidation of apoA-I impairs HDLs RCT and anti-inflammatory functions (865)