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Until other studies are done, Miller recommends those who are co-prescribed to these drugs to observe vitamin B 12 status and take vitamin B 12 supplements if needed [93]

Regarding the results of all of these studies, they found a dose-response relationship between serum homocysteine and the odds ratio of ischemic heart disease, supporting the idea that homocysteine is a causal risk factor for cardiovascular disease

Elevated levels of certain compounds may indicate dysbiosis and increased metabolic stress, which can indirectly affect neurotransmitter balance, mitochondrial function, and neuroinflammatory pathways