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The Interplay of Oxidative Stress and Cobalamin in MS Management Oxidative stress, characterized by a discrepancy between the formation of reactive oxygen species (ROS) and the ability of antioxidant defenses to neutralize them, has been linked to the pathophysiology of MS by inducing inflammation, demyelination, and neurodegeneration [109]

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4.2 Data quality and scale constraints The development of reliable prediction models relies heavily on a large volume of high-quality data, including individuals baseline biostatistical information and real-time physiological parameters