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The FDA evaluation found insufficient evidence to establish effectiveness for the nominated use and highlighted gaps in physicochemical characterisation, immunogenicity and safety information

Liraglutide is the first drug in this class approved by the FDA and is considered the predecessor to new GLP-1 medications

These results project that retatrutide may have a greater efficacy than tirzepatide and semaglutide due to its triple action at GLP-1, GIP, and glucagon receptors

Studies have shown that bevacizumab, as a VEGF inhibitor, has demonstrated neuroprotective effects in several models of TBI (Genovese and Impellizzeri 2022)