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Direct impact can shear peptide bonds through mechanical force, damaging the compound before it even dissolves

More studies on their long-term use are needed

Is well know that ROS presence does not have to be considered only as a harmful effect: experimental research has extensively demonstrated that in physiological conditions ROS signaling as a second messenger in cells is crucial for a variety of biological actions, such as gene expression, signal transduction, and receptors activation [12-13], and also wound healing, tissue regeneration and protection from pathogens [14-15]

Among them, the CYP2 subfamily is the largest, comprising 36 members, of which only 16 encode catalytically active enzymes