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During necrosis, excessive Ca 2+ inflow causes mitochondrial calcium overload, and ROS destroys lipid, protein, and DNA structures, which jointly lead to disordered ionic equilibrium and mitochondrial dysfunction

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To further evaluate formulation properties, we assessed in vitro release and storage stability with different DBP formulations

[DOI] [PubMed] [Google Scholar] Ricciardi A, Elia AR, Cappello P, Puppo M, Vanni C, Fardin P, Eva A, Munroe D, Wu X, Giovarelli M, Varesio L