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[DOI] [PMC free article] [PubMed] [Google Scholar] 105.De Jesus Perez V.A

When damaged mitochondria is unable to maintain their membrane potential, it needs to be degraded through mitophagy ( Mitophagy mainly consists of PTEN-induced kinase 1 (PINK1)/parkin RBR E3 ubiquitin-protein ligase (Parkin)-mediated and receptor-mediated mitophagy (Xiao et al., 2017

Methods: An immunosuppression protocol of early conversion to mTORi with discontinuation of CNI at 12 weeks was initiated in all eligible LT recipients