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Liver Disease and Endocrine Versus Paracrine/Autocrine IGF-1 Production In children with severe liver disease, there may be similar discrepancies between circulating endocrine levels of IGF-I and IGF-I activity in peripheral levels contributed by paracrine/autocrine secretion of IGF-I (94)

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This protein is responsible for intracellular iron storage, but is also important for the regulation of the cellular iron metabolism as well as the intracellular free iron concentration [7], and it is also involved in cellular protection against oxidative stress [8]

When the spine or joints in the arms and legs do not move properly, the brain receives less accurate information about body position