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Early signs can appear as young as 12 to 18 months

Injection technique to ensure subcutaneous delivery: Important safety reminders : Never share pens or needles with others, even if the needle is changed [1] Use each needle only once and dispose of properly in a sharps container Store unused pens in the refrigerator according to label instructions If you miss a dose, follow the specific instructions in your medication's FDA-approved labeling Do not attempt to administer an extra dose if you suspect improper injection Special considerations : Upper arm injections with Wegovy often require assistance from a caregiver

Ruxolitinib is a JAK inhibitor that can be administered topically

2017;39(Suppl 1):98-103