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Vitamin B12 is important for making red blood cells and keeping nerves healthy

Elderly : Older adults often have reduced B12 absorption and may need supplementation

It also plays a critical role in the activation of Yap1 caused by H 2 O 2 (Yaakoub et al., 2022)

Activation of Ret triggers two key signaling pathways: the PI3K/Akt pathway directly inhibits the mitochondrial translocation of the pro-apoptotic protein Bax, and the MAPK/ERK pathway enhances mitochondrial biogenesis by upregulating peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), and the Src kinase pathway is involved in regulating the survival and axonal regeneration of dopaminergic neurons [70]