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A deficiency in carnitine can be caused by an inadequate intake, excess loss through diarrhea or dialysis, liver disorders, the use of certain medications, and some genetic disorders

Mechanisms of PLGA-based nanoparticles transport across the BBB The transport of PLGA-based nanoparticles across the BBB is mediated by active or passive transporters 118

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Exogenous sources of free radicals include environmental factors such as ultraviolet (UV) radiation, ionizing radiation, tobacco smoke, pollution, and exposure to certain chemicals and drugs [24]