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Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction

Four fundamental, intimately related, and interdependent processes are responsible for cell life: survival, proliferation, differentiation, and death (Danese et al., 2021)

In addition, biologically active compounds that can inhibit or induce PCD may serve as key elements for the treatment of this disease

An additional possibility is when acetyl-CoA is derived from amino acids catabolism, such as isoleucine, leucine, threonine, tryptophan, tyrosine, and lysine (Fig