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More recently, it has been considered that curcumin exerts a variety of pharmacological actions through inhibition of inducible nitric oxide synthase (iNOS) as well as its potential as radical scavenger (Elseweidy et al., 2008) Thus, the previously proposed mechanisms for antiulcerogenic effect of curcumin (Yano et al., 2000), such as inhibitory effect on gastric secretion, cytoprotection, antioxidant activity and inhibition of mast-cell degranulation, need to be evaluated again

Ethacrynic acid is an orally active diuretic

Previous reports have shown that relatively high levels of mTOR complex 1 (mTORC1) signaling prevail in MZB 36,37 , but that the maturation of FoB downregulates the mTORC1/Akt pathway 38

Mild side effects may include nausea, headache, abdominal discomfort, or temporary skin rashes